A recent study by UCLA Health has uncovered a significant relationship between perceived loneliness and brain activity related to cravings and motivation towards eating, particularly high-calorie foods such as sugary items. Conducted by Arpana Gupta, PhD, co-director of the UCLA Goodman-Luskin Microbiome Center, the study delves into the intricate connections between social isolation, eating habits, and mental health, especially in the context of remote working conditions post-COVID-19 pandemic.
Dr. Gupta’s research aims to explore the negative impacts of loneliness and how the brain’s response to social isolation influences eating behaviors and mental health. Previous studies have established a link between obesity and mental health issues such as depression and anxiety, and it is well-known that binge-eating can serve as a coping mechanism for loneliness. However, Gupta sought to investigate the specific brain pathways involved in these associations, providing a more detailed understanding of how loneliness affects health outcomes.
“Researching how the brain processes loneliness and how this is related to obesity and health outcomes hasn’t been done,” Gupta noted, emphasizing the novelty of her study, which was published in JAMA Network Open.
The study involved 93 women who were surveyed about their support systems and feelings of loneliness and isolation. Based on their responses, the participants were divided into two groups: those with high perceived social isolation and those with low perceived social isolation. The researchers observed that women with higher levels of social isolation exhibited higher fat mass, poorer diet quality, greater cravings, reward-based eating, uncontrolled eating, and increased levels of anxiety and depression.
To further explore these observations, the researchers showed the participants various images, including food versus non-food, sweet food versus non-food, and savory food versus non-food. MRI scans were used to record the participants’ brain activity while they viewed these images.
The study revealed several crucial insights:
Dr. Gupta explained that these findings align with what is intuitively understood about loneliness and eating behaviors. When individuals feel lonely, it affects more than just their emotional state; it impacts their eating habits and cravings, particularly for unhealthy foods. This can lead to a vicious cycle where increased cravings lead to more eating, which in turn exacerbates anxiety and depression, further driving unhealthy eating behaviors.
“If you have more cravings, you eat more and may have more anxiety or depression, which may lead you to eat more,” noted Xiaobei Zhang, the study’s lead author and a postdoctoral researcher. This cyclical pattern underscores the complex interplay between loneliness, eating behaviors, and mental health.
Looking ahead, Dr. Gupta plans to expand her research to include other biological markers such as metabolites, microbiome, and inflammatory signatures associated with loneliness. This comprehensive approach aims to deepen the understanding of how loneliness affects the body and mind, potentially leading to more effective interventions for improving mental and physical health outcomes.
The UCLA Health study provides critical insights into the impact of loneliness on brain activity, eating behaviors, and mental health. The research highlights the importance of addressing social isolation and its effects on individuals’ well-being, especially in the context of increasing remote work and social distancing measures. By emphasizing the role of holistic interventions and healthy lifestyle choices, the study offers valuable guidance for individuals and healthcare providers seeking to mitigate the adverse effects of loneliness.
Overall, the study by Dr. Gupta and her team underscores the need for a multidisciplinary approach to tackling the intertwined issues of loneliness, unhealthy eating behaviors, and mental health, paving the way for more comprehensive and effective treatments in the future.
Source: Materials provided by University of California – Los Angeles Health Sciences. Original written by Kelsie Sandoval. Content edited for style & length.